Progressive Multifocal Leukoencephalopathy Complicating X-linked Hyper-IgM Syndrome in an Adult
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چکیده
منابع مشابه
Polyomavirus-Associated Progressive Multifocal Leukoencephalopathy (PML) in HAART era
Polyomaviruses may cause human disease, particularly in immunocompromised hosts. JCV, one of the members of polyomaviridae family, is the causative agent of the neurological disease progressive multifocal leukoencephalopathy (PML), which occurs mostly in immunocompromised patients. Progressive Multifocal leukoencephalopathy (PML) is a progressive demyelinating disorder of the central nervous sy...
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A 69-year old man presents with a subacute history of worsening confusion, anxiety and abnormal gait. Brain MRI revealed an extensive non-enhancing signal abnormality of parieto-occipito-temporal white matter. CSF PCR was positive for JC virus, suggestive of progressive multifocal leukoencephalopathy (PML). Extensive workup for occult immunosuppression was negative. Although PML in an immunocom...
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Progressive multifocal leukoencephalopathy (PML) is a demyelinating brain disease caused by Jamestown Canyon virus (JCV). This disease is an important cause of morbidity and mortality in acquired immunodeficiency syndrome (AIDS) patients. We report a 34-year-old man infected with HIV-1 who presented with frequent general tonic clonic seizure and left side weakness for 2 months. Clinical feature...
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Progressive multifocal leukoencephalopathy in an immunocompetent patient Nicolien M. van der Kolk, Peer Arts, Ingeborg W. M. van Uden, Alexander Hoischen, Frank L. van de Veerdonk, Mihai G. Netea & Brigit A. de Jong Department of Neurology, Radboud University Medical Center, Nijmegen, The Netherlands Department of Genetics, Radboud University Medical Center, Nijmegen, The Netherlands Department...
متن کاملProgressive Multifocal Leukoencephalopathy
Before embarking on experimental therapies for progressive multifocal leukoencephalopathy (PML), the diagnosis needs to be unequivocally established. Improving the underlying immunodeficiency state is the best initial approach to the management of PML. Immunosuppressive therapies should be discontinued when feasible. In the patient with AIDS, highly active antiretroviral therapy should be admin...
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ژورنال
عنوان ژورنال: Internal Medicine
سال: 2006
ISSN: 0918-2918,1349-7235
DOI: 10.2169/internalmedicine.45.6023